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Twenty-six years ago, book lovers and science geeks everywhere bought Stephen Hawking’s A Brief History of Time, his attempt to make cosmology understandable for the layman. The book made the astrophysicist a rock star among scientists, a legend that continues to fascinate not just for his big brain, but also for his very survival. Diagnosed with Amyotrophic lateral sclerosis (ALS aka Lou Gehrig’s Disease) when he was only 21, Hawking was given two years to live. He’s now 72.

Premiering at the Toronto International Film Festival on September 7th and in theaters on November 7th, The Theory of Everything relates Hawking’s story as a young man who does not let a horrible disease prevent him from working on his theories or stop him from falling in love with fellow Cambridge student Jane Wilde. Directed by James Marsh (Man on Wire, Shadow Dancer), the film stars Eddie Redmayne and Felicity Jones.